Loved the books, have them and read them many times.
However, you do not explain why being hooked up to the various systems makes them think faster. They are still a Gartagen in a body, connected. If you are going with the concept that Anne had, you should have brute force data crunching relegated to other computers, that are under the subjects control.
Also why would anyone with a healthy body want to give it up to become a computer?
And you never say what happens to "with a seventy percent wash out rate," the ones who are washed out?