No, it's not hard.
WARNING: BEFORE YOU TOUCH ANYTHING IN YOUR COMPUTER MAKE SURE TO HOLD AS MUCH OF YOUR HANDS (especially fingers) AS POSSIBLE AGAINST THE METAL FRAME OF YOUR MACHINE FOR A FEW MINUTES! If you don't, you could fry some of your computer parts with electrostatic changes built up in your fingers. Also, try to keep your arm against the metal frame as you mess with things.
Also, and this is common sense, but don't forget to unplug the thing first, and definately don't do this while your box is running.