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I think it's NPC, and I think it's okay to use as a villain. The Black Syndicate is historically known for selling guns (Zen Arms is their guns wing) and drugs.
I am interested in doing things with the Syndicate as well. They may be frenemies with my character's mercs. The organization could use some fleshing out. Is it okay to add things to the lore or does that need to go through the NTSE?